Gene Therapy Set to Make a Deaf Ear Singing

The days are not faraway, if an Oregon team is to beThey performed the gene therapy , on that unborn
believed, when a deaf can be seen listening to themouse, using a harmless virus. The key genes,Atoh1,
chart busters and enjoying symphonies and he mayrelated to hearing ability, were inserted into cells to
,also, be seen dancing to many tunes.produce the cochlear hair cells .
Most probably, dancing to the tunes of a certain gene,The experts found the newly developed cells no less
which the scientists believe can bring back the lostuseful than the natural cochlear hair cells . As the
hearing ability.hearing ability of the mouse was found pretty normal.
The scientists have shown success in reproducingHowever, this therapy, still not done on any human
cochlear hair cells. These cells are efficient convertersbeing, is the first of its kind which may prove helpful to
of sound waves into electric signals. These signalsreproduce or repair cochlear hair cells.
after reaching brain turn into things what we hear orSignificantly, if this therapy comes favorable, the use of
listen to.any mechanical or electrical devices can be forbidden
Any damage to these hair cells lead to hearingin the treatment of damaged cochlea.
impairment. These hair cells are mostly damaged byMoreover, seeing the result of the early experiments, it
the continuous and elongated exposure to harsh andis very likely that it will work on humans too. That's
loud noise.why the researchers at Oregon said, "This capability is
The medical professionals, once completely clueless,a crucial first step in defining translational therapies to
had been trying hard to come up with a solution toameliorate the effects of inner-ear disease in humans."
bring an end to this damage. The recent breakthroughAt present, the only treatment for hear loss, cochlear
has shown many rays of hopes to millions of hearingimplant, is not capable of bringing back the hearing to
impaired around the globe.its normalcy. It provides only a minimized version of the
The experiment, on an unborn mouse, by the medicalsound sensations.
experts of Oregon Health and Science UniversityHopefully, a deaf will have his hearing days back with
became fruitful when it converted a different cell into athe normal and maximized sound sensations, may be
specific cochlear hair cell. The team is led by Johnvery soon.
Brigande.